产品货号:
Z38051
中文名称:
FH抗体
英文名称:
Anti-FH Antibody (Clone#OTI1F10)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-FH Antibody (Clone#OTI1F10) |
指标别名 | FH;Fumarase;fumarate hydratase;HLRCC;LRCC;MCL;MCUL1 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat,dog |
应用范围 | WB,IHC,IF,FCM |
基因名称 | FH |
克隆号 | OTI1F10 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Full length human recombinant protein of human FH (NP_000134) produced in HEK293T cell. |
实际分子量 | 50.2KD |
成分 | PBS (pH7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
背景资料 | Fumarase (or fumaratehydratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate.Fumarase comes in two forms:mitochondrial and cytosolic.The mitochondrial isoenzyme is involved in the Krebs Cycle (also known as the Tricarboxylic Acid Cycle [TCA] or the Citric Acid Cycle),and the cytosolic isoenzyme is involved in the metabolism of amino acids and fumarate.Subcellular localization is established by the presence of a signal sequence on the amino terminus in the mitochondrial form,while subcellular localization in the cytosolic form is established by the absence of the signal sequence found in the mitochondrial variety.This enzyme participates in 2 metabolic pathways:citric acid cycle,reductive citric acid cycle (CO2 fixation),and is also important in renal cell carcinoma.Mutations in this gene have been associated with the development of leiomyomas in the skin and uterus in combination with renal cell carcinoma. |
Uniprot ID | P07954 |
基因名全称 | fumarate hydratase |
蛋白名全称 | Fumarate hydratase,mitochondrial |
推荐稀释比 | Western blot (WB) 1:1000 Immunohistochemistry in paraffin section (IHC) 1:50 Immunofluorescence (IF) 1:100 Flow cytometry (FCM) 1:100 |
相关搜索:FH抗体,FH单抗,Anti-FH Antibody (Clone#OTI1F10)